Endocrine Abstracts

Introduction: Neurofibromatosis type 1 (NF1) is one of the most frequent genetic dominant syndrom in men with a prevalence of 1 in 2600 to 3000 individuals worldwide. NIH NF1 diagnostic criteria are driven by the most frequent manifestations of the disease (café au lait macules (CAL), neurofibromas, freckling, optic glioma, Lisch nodules and osseus lesions). There are many clinical manifestations of NF1 (neurological, cardiovascular, gastrointestinal, endocrine and orthop...

Introduction: Pheochromocytoma and paraganglioma (PPGLs) are rare neuroendocrine tumors. Some of them are catecholamine-secreting tumors responsible for hypertension or adrenergic symptoms. Among 10% are malignant with a higher rate of malignancy in the inherited syndromes. Management of patients with hereditary pheochromocytoma and PPGLs is well defined and standard treatment is surgical resection.Case report: We report the case of a 53-year-old man who...

Introduction: Neurofibromatosis type 1 (NF1) is one of the most frequent genetic dominant syndrom in men with a prevalence of 1 in 2600 to 3000 individuals worldwide. NIH NF1 diagnostic criteria are driven by the most frequent manifestations of the disease (‘café au lait’ macules (CAL), neurofibromas, freckling, optic glioma, Lisch nodules and bone lesions). There are many clinical manifestations of NF1 (neurological, cardiovascular, gastrointestinal, endocrine ...

Introduction: Primary adrenal lymphoma is rare, representing less than 1% of non-Hodgkin lymphomas.1 The clinical presentation is non-specific, symptoms of adrenal insufficiency may occur with bilateral lesions, and work up can be tricky.2Background: A 60-year-old man was admitted mid-January 2020 for acute left abdominal pain. He had no medical history and didn’t smoke or take any medication. He had no history of recent trauma...

We present the case of an octogenarian with a major history of lambda light chain myeloma which was treated by a first-line lenalidomide and dexamethasone from June 2018 to September 2019. Patient had also hypertension and valvular heart disease (mechanical valve and anticoagulation by acenocoumarol). In September 2019, a right adrenal mass was incidentally discovered by a renal ultrasonography made for acute kidney injury. The abdominal CT-scan confirmed the presence of a lar...

Introduction: Aberrant expression of serotonin receptors has been described to be involved in the pathophysiology of both aldosterone-producing and cortisol-producing adrenal adenomas.Case report: A 46-year-old woman was referred for evaluation of severe hypertension associated with hypokalaemia. Primary aldosteronism with concurrent subclinical Cushing’s syndrome was diagnosed. A CT-scan identified a lesion of 4 cm in the right adrenal gland and a ...